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by
Eva Tang
May 14, 2025
· Updated on
AI and email management go hand in hand.
There are AI tools dedicated to helping you clean your inbox (like SaneBox) and plenty that help you draft emails better and/or faster.
In a world where new AI tools are releasing every day, we're going to share some practical ways to use AI within email and your inbox.
At the end of each section, we'll cover some of the best AI email tools and AI assistants that can help you be more efficient in your inbox—whether you're a Gmail or Outlook user.
Here at Missive, our users get a lot of emails—100+ in a day in some cases. We crowdsourced the most practical, helpful AI suggestions that real businesses are using to maintain a clutter-free, productive inbox.
Before we jump into the examples, these are the three broad buckets where AI is used within inboxes:
For cleaning emails, there is usually a deep purging functionality (i.e., archive all emails before a certain date) as well as a new system to keep your inbox clean after the purge (i.e., auto-categorization into folders/labels). Clean Email is a great example of this bucket.
For drafting and writing emails, you can create prompts that take into consideration your writing style, structure, and tone and add in resources for AI to pull context from—most commonly, your knowledge base or website.
For kicking off other tasks—this is the most exciting part of AI within your inbox. Certain tools (like Missive's AI-powered rules) allow you to automate a set of actions based on the context of an email. Imagine every email gets assigned to the right people, a set of tasks is created, a label or folder is applied, and an entry is made in your CRM—without a single human interaction. That’s magic!
Let's get to the AI-powered magic.
We're highlighting Missive's AI-powered rules in the examples below, but you can create your own AI email automations with your favorite tools, and we include some recommendations.
Here are the 6 best AI email workflows.
Our inboxes get inundated every day, but not every email deserves equal attention. A clean inbox needs a system of categorization.
Historically, you could set up automations based on sender, message content, etc.—but now with AI, you can understand the context of emails, which changes email management entirely.
It's like having an AI assistant read each email and then categorize it based on the context within. It's far more robust than just looking at the sender domain.
If you don't already have some form of auto-labeling, auto-folder categorization, or archiving automation running, here are a few examples to get you started:

By auto-filing certain emails out of your inbox using AI, you'll be able to focus on the ones that need your attention. And when you have some free time, you can visit your newsletter label to catch up on industry insights.
Most modern email clients have some version of this built in. If you're looking for an add-on tool for Gmail or Outlook, we cover those below as well.
Missive — Inbox collaboration for teams
Superhuman — Great for keyboard shortcut lovers
Shortwave — For an AI-first inbox
SaneBox — AI email organizer that integrates with your existing client
Unroll.me — Alternative to SaneBox, bulk email cleaner for any provider
AI can save time inside your inbox—but using it to trigger external workflows is where the magic really happens.
Example: A real estate business receives emails from both buyers and sellers in a shared inbox. Their workflows are completely different, so we used AI to identify the intent and trigger specific assignments, tasks, and summaries for the right team members.
If you have different workflows depending on the email, you can use AI to detect the context and automate accordingly.

Relay.app — AI-first workflow builder
Zapier — Classic builder, now with AI
Missive — AI rules built into the collaborative inbox
Inbox maintenance is like pruning a tree—it requires regular attention.
With AI clients, workflow builders, or Missive rules, you can automatically clean up emails without manually clicking "unsubscribe."
Set it up narrowly (specific senders or domains) or broadly (based on open behavior, like emails unread for 30+ days).

Solutions like SaneBox include versions of this, though some manual training may be required.
Say you run an accounting firm where each client has a dedicated team and inbox.
Most messages are about invoices, but occasionally, an urgent email from the CEO arrives that needs management's attention.
AI can identify urgency and escalate the message automatically to the right person.

Other tools can do this too—but may require you to create specific folders/labels and rely on manual monitoring.
This works best if you have a large, public knowledge base or help center that the AI can reference. If you do, you can use one of the newer AI models that allow you to search the web.
Here's the prompt we use at Missive for our support team:
You are an expert customer support specialist for Missive, the collaborative team inbox platform. Your job is to draft accurate, empathetic, and clear replies to customer inquiries based only on official Missive documentation.
Note: Keep all responses strictly tied to Missive's documented functionality.
Now, if you want to get crazy with it. You can create an automation where a draft is created every time an incoming email fits a specific criteria. And you can use AI to help you determine which email triggers the automation.

Don't want to pay for contact enrichment tools? Use AI to summarize new prospects.
It adds context directly to the email thread, so you can start conversations better informed.

For more robust enrichment, tools like Clay or CRMs like HubSpot and Salesforce offer AI-powered data collection.
We hope these ideas help you clean emails, draft faster, and automate smarter.
All the tools mentioned above offer a “fresh start” feature to deep clean your inbox and begin anew.
Whether you're using SaneBox with your current client or switching to an AI-first inbox—there's no reason your email shouldn’t flow to the right people and places automatically after setting a few AI-powered rules.
If you're looking for an AI-powered email client uniquely designed for teams—give Missive a try. No credit card needed, and our free trial includes access to AI rules.